Pathway in Gastric Epithelial Cells IL-8 Secretion via the TLR4-Dependent GroES Are Critical for Helicobacter pylori The C-Terminal Disulfide Bonds of Hsu, Shuei-Liong Lin and Lu-Ping Chow
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منابع مشابه
Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production
Helicobacter pylori infection is associated with the development of gastric and duodenal ulcers as well as gastric cancer. GroES of H. pylori (HpGroES) was previously identified as a gastric cancer-associated virulence factor. Our group showed that HpGroES induces interleukin-8 (IL-8) cytokine release via a Toll-like receptor 4 (TLR4)-dependent mechanism and domain B of the protein is crucial f...
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تاریخ انتشار 2015